Genetics and Depression
It’s never been clear why certain individuals are more vulnerable to depression or why some medications or other treatments such as electrical stimulation of the brain work for some but not others. Although environmental and social factors play a major role in many cases of depression, genetics are also now known to be crucially important.
However, though researchers are now looking at our genes to get some answers, depression has proven largely resistant to this approach. A recent analysis of the DNA of 300,000 people in the UK, the biggest of its kind, identified almost 80 genes that could be involved in depression though some particular genetic mutations have been identified as definitely increasing the risk of a disorder.
Another direction – and one that is much more practically applicable to use in treating depression – is AI (Artificial Intelligence). By using a large database of information on age, gender, education, origin, occupation, and anything else that they find relevant, along with someone’s DNA , we can predict who will respond positively to particular treatments and that is the model used by the Predictix system.